Single-electron transmetalation: An enabling technology for secondary alkylboron cross-coupling
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Tarih
2015Üst veri
Künye
Primer, D. N., Karakaya, I., Tellis, J. C.,Molander, G. A., (2015). Single-electron transmetalation: An enabling technology for secondary alkylboron cross-coupling. Journal of the American Chemical Society, 137(6), 2195-2198. DOI: 10.1021/ja512946eÖzet
Single-electron-mediated alkyl transfer affords a novel mechanism for transmetalation, enabling cross-coupling under mild conditions. Here, general conditions are reported for cross-coupling of secondary alkyltrifluoroborates with an array of aryl bromides mediated by an Ir photoredox catalyst and a Ni cross-coupling catalyst.