Calculation of Production Reaction Cross Section of Some Radiopharmaceuticals Used in Nuclear Medicine by New Density Dependent Parameters

Abstract

In nuclear medicine, radiopharmaceuticals are used for diagnosis or treatment purposes. Radiopharmaceuticals containing radionuclide in their structure are produced by reactors, generators or cyclotrons and are generally used for scintigraphy or tomographic investigations. The produced radionuclides can be given to the human body together with organic or inorganic substances. In this study, the production reaction cross sections were calculated for two selected radiopharmaceutical nuclei (99Tc and 115In) using the semi-empirical cross section formula for the (n,) reactions developed by Tel et al. (2008). The density depending on (n, α) reaction cross sections were also investigated with the four Skyrme Hartree Fock parameters (S3, T3, SKM and SKM*). While the calculated value from the semi-empirical formula developed by Tel et al. (2008) gave reasonable results, the density-dependent calculations were observed lower values than that of experimental values.