3-Aminoquinazoline-phosphine ligands and their ruthenium(II) complexes: application in catalytic hydrogenation and transfer hydrogenation reactions

Abstract

3-Aminoquinazolinone-phosphine proligands (5a-e) and their Ru(II) complexes (6a-e) were prepared and characterized by NMR (H-1, C-13, P-31{H-1}), FTIR and microanalysis. The 3-aminoquinazolinone-phosphine ligands were found to coordinate with the Ru(II) center via their phosphorus and nitrogen atoms. The Ru(II) complexes were applied as catalysts for the hydrogenation and transfer hydrogenation of prochiral ketones. The results showed that these complexes are efficient transfer hydrogenation catalysts.